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Continuing Medical Education
41 (
3
); 340-344
doi:
10.25259/IJNM_36_2026

Essentials of Engineering in Establishing Nuclear Medicine Centre

Department of Nuclear Medicine, Apulki Medical Centre, Baner, Pune, Maharashtra, India

*Corresponding author: Hasmukhkumar Mangilal Jain, Department of Nuclear Medicine, Apulki Medical Centre, Baner, Pune, 411045, Maharashtra, India. drhasmukhjain@ymail.com

Licence
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Jain HM. Essentials of Engineering in Establishing Nuclear Medicine Centre. Indian J Nucl Med. 2026;41:340-4. doi: 10.25259/IJNM_36_2026

Abstract

Engineering is often perceived through large visible infrastructures; however, some of its most impactful contributions occur silently within healthcare facilities. The nuclear medicine centre represents one of the most intricate intersections of engineering and clinical medicine. Their successful establishment depends on the seamless integration of civil, electrical, mechanical, architectural and information technology disciplines, all operating within a stringent radiation safety framework. The design and execution of such facilities are governed by regulatory requirements laid down by the respective country’s regulatory authority, which in India is Atomic Energy Regulatory Board. The role of engineering is to create a safe, efficient and patient-centric nuclear medicine centre, emphasising regulatory compliance, operational workflow and future-ready design.

Keywords

AERB
Engineering
Facility design
Nuclear medicine
Radiation safety

OVERVIEW

Engineering is often thought of as roads, bridges, buildings, skyscrapers, aeroplanes, rockets or monumental works that shape the skyline and capture imagination. However, some of the most life-changing engineering achievements happen quietly, away from public view, in places designed for healing. One of the most complex and fascinating examples is the nuclear medicine centre, which is a facility where advanced imaging and therapy are conducted using radioactive isotopes to diagnose and treat disease.[1-3] Establishing a nuclear medicine centre is far more than constructing a hospital wing, and it is like an orchestration of disciplines involving science, engineering and human empathy.[1,2] It is at the intersection of cutting-edge medical science and uncompromising safety standards.

In India, building a nuclear medicine centre is not merely a matter of installing machines in a building. It is an intricate symphony of civil engineering, electrical engineering, architectural design, IT integration and safety systems whereby all are aligned with strict regulatory guidelines from atomic energy regulatory board (AERB). Behind the seamless imaging experience lies a world of meticulous engineering whereby each wall, pipe, cable and sensor is there for a reason, born out of regulatory compliance, patient comfort and decades of nuclear safety science.[1-4] Every engineering decision here matters because a mistake does not just mean equipment failure; it could mean a breach in radiation safety, patient well-being, or environmental security.[1-3]

Civil engineering aspects

Civil engineering is the bedrock, literally, of a nuclear medicine facility. Unlike a conventional hospital unit, the civil works here must accommodate the triple demands of heavy medical machinery, radiation shielding and high-sensitivity imaging.[1,4]

The civil engineering process begins with site selection. In India, this is guided not only by urban planning laws but also by AERB stipulations that require certain separations between radiation zones and public areas.[1] Geotechnical surveys assess the soil bearing capacity (SBC) that is crucial for supporting heavy equipment weighing in tonnes, such as a PET-CT scanner and a Cyclotron vault. Soil testing is critical as poor load-bearing soil requires a pile foundation or a raft foundation.[5,6] Seismic zone considerations are vital in earthquake-prone zones like the Himalayan belt or the state of Gujarat. As per IS 1893 (Criteria for Earthquake Resistant Design of Structures i.e. the principal structural code published by the Bureau of Indian Standards) India’s earthquake zones require a different structural design.[7] Water table levels are important for centres being constructed in the basement of the building or for constructing underground delay tanks.[1,8]

Positron emission tomography-computed tomography (PETCT) and single photon emission computed tomography (SPECT) scanners require vibration-free operation for accurate imaging.[9,10] For this, the Civil engineers design reinforced concrete floors with vibration damping, sometimes isolated from the main building’s structural frame.[10,11] For this, engineers pay special attention to dead load using high-density shielding concrete (up to 3.5 g/cm3 with barite), load path to ensure equipment weight does not overstress slabs, slab deflection control to maintain scanner alignment and dynamic loads (rotating gantries in PET/SPECT scanners).

Shielding is not “added on” but is built into the structure. Engineers integrate high-density concrete walls, almost 230 mm thick, for the PET-CT department and lead-lined partitions and doors as per AERB dose rate limits (<1 µSv/hr at 1 m from the surface).[1,4,12]

Drainage systems must be integrated early in the civil design so as to handle radioactive wastewater in the future. Waterproofing is crucial to prevent seepage, especially in the basement, since any leakage could result in costly contamination and environmental hazards.[1,8,13]

Civil engineers need to ensure that the load-bearing elements do not interfere with the workflow. For this, they need to see that no structural column is present in the patient scanning room that can obstruct the gantry rotation, that the floor levels are aligned to allow wheelchair and stretcher movement without a ramp and also ensure that all the trenches are covered with metal covers.

Engineers also have to ensure that the corridors are wheelchair-friendly with at least 1.5 metres in width, have automatic sliding doors in controlled areas for reducing hand contact and contamination spread, use soft colour palettes in waiting areas for reducing patients’ anxiety and involve daylight integration in non-supervised areas and artificial lighting in the shielded controlled areas. Engineers ensure the usage of polypropylene or stainless-steel pipes that are resistant to radioactive contamination, and also that there are separate drainage lines for radioactive and non-radioactive effluent.[1,8,13] They design underground shielded delay tanks in such a way that radioactive waste can be stored until it decays to below permissible discharge levels. They also install automatic level sensors that can trigger an alert to the facility manager when a particular tank approaches near full capacity, along with a remote monitoring system for assessing log-fill levels and decay times. End-users will then need to test the effluent before releasing it into the municipal systems, complying with AERB Safety Code AERB/RFMED/SC-1.

For fire safety purposes, engineers use fire-resistant construction materials like non-combustible wall panels in the hot labs and fire-safety rated doors with self-closing mechanisms.[14] For fire detection purposes, they use an addressable fire alarm system integrated with the hospital safety network. For fire suppression purposes, they use inert gas in the equipment room so as to avoid water damage. Engineers also design an evacuation plan with special routes so as to avoid contamination zones. End-users are required to train their staff in both fire and radiation safety protocols at regular intervals.

Engineers ensure that medical gas pipeline system (MGPS) lines supplying oxygen, air and vacuum are installed and tested for any leakage before commissioning, place alarm systems to alert users in case of leakage or failure, as well as place valves at appropriate places, which, in case of leakage or failure, can be closed in an emergency. It is ensured that vendors supplying medical gases do so uninterruptedly to the nuclear medicine centre.[15]

Electrical engineering aspects

Electrical engineering in a nuclear medicine facility is much more than just supplying electricity. It is about delivering stable, clean and uninterrupted power to some of the most sensitive and expensive equipment in healthcare.[16,17]

Equipment like PET-CT, SPECT / SPECT-CT, cyclotron, dose calibrator, fume hood, etc., relies on precise voltage regulation to operate safely and deliver accurate results. Even a brief voltage fluctuation can lead to expensive downtime or, worse, compromised patient scans.[16-18]

Electrical engineers do a thorough load analysis as the first step, taking into account static load for overall lighting, heating, ventilation and air-conditioning (HVAC) and information technology (IT) systems, dynamic load for scanners, cyclotron, fume hood, etc. and critical load for imaging electronics that require < ±2% voltage variation. For example, a PET-CT system may require up to 50–60 kVA dedicated power supply, whereas a cyclotron may require up to 150–200 kVA with a three-phase power supply.

The basic need of a nuclear medicine imaging system is that it requires an uninterrupted and clean power supply. For this, electrical engineers design dedicated transformers to isolate sensitive imaging equipment from hospital-wide electrical noise and provide a double-conversion online UPS system for continuous power to scanner computers, image acquisition systems and hot lab automation, as well as prevent scan interruption during grid failures. General requirement for a typical nuclear medicine department includes uninterruptible power supply (UPS) capacity sized at 125-150% of critical load, battery backup of 15-30 minutes to allow generator startup, separate UPS systems for scanners, dose calibrators and IT servers, typically with 30 minutes to 1 hour autonomy and automatic transfer switches (ATS) for instant switchover to diesel generators during outages. Also, there should be a dedicated fire partition between the UPS and the batteries.

Another important aspect is earthing and bonding, as proper earthing ensures electrical safety for staff and patients, and proper electromagnetic compatibility (EMC) avoids interference with sensitive electronics. Copper strips and copper pipes are used for earthing purposes. Radiation dose calibrator and gamma camera are bonded to the same earth grid as shielding structures to prevent potential differences.

For lighting design purposes, electrical engineers consider installing low-glare fixtures in imaging rooms to prevent light reflections on monitors, making provision for task lighting in a hot lab with adjustable intensity for precise work and providing emergency lighting integrated with UPS for safe evacuation during power failure. They provide separate conduits for high-voltage, low-voltage and data cabling to avoid interference, use shielded cables for critical signal lines, make provision for redundant network cabling to ensure zero downtime for picture archiving and communication systems (PACS) and radiology information system (RIS) systems and provide trenches and metal covers to protect the cable wires.

Architectural engineering

In nuclear medicine, architecture is not just about arranging rooms; it is about designing a precise choreography of people, equipment, air and materials. The architectural blueprint must consider safety regulations from AERB, operational efficiency, patient psychology and aesthetic appeal.[1,19]

Functional zoning is done to keep clean and contaminated zones apart. The facility layout revolves around zoning principles that are divided into controlled areas, such as hot lab, radio pharmacy and radioactive waste storage rooms, supervised areas, such as radioactive dose administration room, uptake room and scanner room and non-supervised areas, such as general waiting area, reporting room and office room. The goal is to maintain a unidirectional workflow in a way that the radioisotope moves from the source storage room to the hot lab/radio pharmacy room to the dose administration room and then either back to the source storage room or directly to the waste storage room. For patients requiring to be injected inside the scanner room, the flow is like a radioisotope/radiopharmaceutical moves from source storage room to hot lab/radio pharmacy to scanner room and then back to hot lab (for taking post-injection counts) or directly to waste storage room. Furthermore, finally, patients injected with radioisotopes/radiopharmaceuticals move from the dose administration room to the post-dose administration waiting room and from there to the scanner room. All this happens without backtracking or contamination crossover.

Shielded room layout

For a nuclear medicine scanner room, engineers design shielding in such a way as to accommodate large equipment (PET-CT, SPECT/SPECT-CT) with gantry clearance, maintain a line of sight between the operator console and patient by using a large-sized lead-glass viewing window[19,20] and also house auxiliary systems like HVAC ducts, oxygen lines and emergency intercoms without any breach in shielding.

A meticulously planned architectural layout ensures a radial workflow, which means that the patient enters through the reception, moves to the uptake room, then to the imaging room and then exits without retracing the contaminated path. For this purpose, a hot lab is generally placed close to the imaging room but isolated from public access.

Flooring in a nuclear medicine department is not just about walking comfort but a frontline safety and hygiene feature.[21,22] Vinyl flooring is preferred because it is seamless and impermeable, i.e., it prevents liquid penetration, it eases the decontamination process, i.e., its smooth surface permits quick clean-up of spills, it is chemical-resistant to decontamination agents, and it is anti-static in nature. It therefore protects electronics, and it is also slip-resistant, which is very important in patient areas. The various types of vinyl flooring that are typically used in a nuclear medicine department are homogeneous vinyl, which is a single-layer constructed vinyl meant for uniform performance and is ideal for high-traffic areas, conductive vinyl that prevents static build-up, which is very essential near sensitive imaging electronics and finally the cushioned vinyl that is used in waiting rooms for patient comfort. During installation of vinyl, coved skirting is done, which ensures that the flooring curves up the wall for elimination of the floor-wall junction crevices where contamination can hide, and the seams are heat-welded, which creates a continuous impervious surface, as even the tiniest unevenness can trap contamination or compromise heavy scanner stability, for which underlayment smoothing can be done. Some architects also suggest colour zoning within the flooring to visually guide staff and patients in the form of red or yellow zones for restricted areas with radioactive work, blue or green zones for patient waiting areas, and grey zones for transitional corridors. This visual safety language helps even non-technical visitors avoid restricted areas instinctively. Vinyl flooring in controlled areas undergoes more frequent cleaning cycles with approved detergents and disinfectants. The typical service life is 10– 15 years, but in nuclear medicine, some hot lab floors are replaced every 7–8 years due to higher wear from chemical exposure.

The architectural plan integrates negative pressure ventilation in the hot lab and fume hood area to ensure radioactive vapours are properly contained. Conversely, positive pressure is maintained in non-supervised areas like the reporting room to prevent contamination ingress. Temperature and humidity control are essential for both equipment performance and patient comfort. High-end PET-CT scanners, for example, require stable environmental conditions to avoid detector drift. Activated charcoal filters are used for air exhaust from isotope handling areas, like a fume hood.[23,24]

Information technology engineering aspects

While electrical engineering delivers power, information technology integration delivers data, and in nuclear medicine, data is everything. The value of the scan lies in how quickly, securely and accurately it can be captured, processed and shared. Proper integration of PACS, RIS and hospital information system (HIS) needs to be done, PACS for storing imaging data for later retrieval and analysis,[25,26] RIS for scheduling, reporting and other workflows and the HIS system that links patient demographics and billing. For a secure PACS server, often redundancy is used in different cities in India to protect against outages.

For network infrastructure in the nuclear medicine department, gigabit Ethernet forms the backbone for rapid image transfer, and virtual local area network (VLAN) segmentation helps in isolating medical imaging traffic from the general hospital network. Additionally, VPN access can be given to nuclear medicine physicians for tele-reporting purposes. Given the sensitive nature of the patient data, IT networks are often segregated from public hospital Wi-Fi and are protected with firewalls, intrusion detection and encryption.[27] They are also end-to-end encrypted for image transfer, a two-factor authentication system is followed for remote logins, regular penetration testing is done to ensure compliance with the Indian IT Act 2000 and also designed with redundant switches and servers for uptime.

Mechanical engineering aspects

The hot lab is designed with lead-lined L-benches for the preparation of radiopharmaceuticals,[28,29] shielded dose calibrators are used to measure patient dose accurately, and a lead glass viewing panel (window) is used between the scanner room and the console for safe visual monitoring. A fume hood is typically provided with a negative-pressure chamber with a dedicated exhaust system, a charcoal filter to capture airborne radioactive iodine and stainless-steel interiors for easy decontamination. Height and reach of work surfaces are designed in such a way as to minimise strain and overall exposure time to the nuclear medicine technologist.

Sustainability and future trends

Today, with climate change concerns, rising energy costs and the ever-increasing demand for healthcare access, there is a push to make nuclear medicine facilities more resource-efficient, adaptable and future-ready, but without compromising on the radiation safety aspect.[30-32] Engineers push for green building practices by using light-emitting diode (LED) lights with motion sensors, high-efficiency HVAC systems, rainwater harvesting, dual plumbing systems, and solar panels for non-critical loads. They incorporate modular and adaptive designs by using prefabricated shielded panels for quick reconfiguration and scalable IT infrastructure for future AI integration. Optimised patient scheduling takes care of both radiation safety and reduces HVAC load. For the future, one can consider cyclotron-linked networks for multiple centres, AI-assisted imaging and tele-nuclear medicine for remote diagnosis.

CONCLUSION

The essentials of engineering in nuclear medicine are that it acts as a silent healer in terms of the usage of reinforced concrete shielding, a delay tank and a UPS system that ensures every scan is safe and accurate. There is a multidisciplinary symphony between civil, architectural, electrical, IT and safety engineering that comes together seamlessly. As far as nuclear medicine centres in India are concerned, their design must be robust, cost-effective, scalable and compliant with AERB regulations. Finally, a nuclear medicine centre is not simply built but engineered, with safety, precision and care for every patient, every time.

Ethical approval:

Institutional Review Board approval is not required.

Declaration of patient consent:

Patient's consent is not required as there are no patients in this study.

Conflicts of interest:

There are no conflicts of interest.

Use of artificial intelligence (AI)-assisted technology for manuscript preparation:

The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript, and no images were manipulated using AI.

Financial support and sponsorship: Nil.

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