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Disseminated Multiple Organ Lymphoma Presented as Vulvar Lesion Diagnosed by [18F]FDG PET/CT
Address for correspondence: Prof. Zehra Pınar Koç, Department of Nuclear Medicine, Mersin University, Mersin, Turkey. E-mail: pinarkoc@mersin.edu.tr
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Received: ,
Accepted: ,
This article was originally published by Wolters Kluwer - Medknow and was migrated to Scientific Scholar after the change of Publisher.
Abstract
We would like to present a 49-year-old female patient who was presented with a vulva lesion and palpable inguinal lymph nodes who were diagnosed with disseminated multiorgan involvement of high grade diffuse large B-cell lymphoma. The 18F-fluorodeoxyglucose positron emission tomography computerized tomography imaging showed multiple cervical, axillary, and abdominal lymph nodes, pulmonary nodules as well as gross hypermetabolic vulvar lesion.
Keywords
Lymphoma
vulva
fluorodeoxyglucose
positron emission tomography computerized tomography
![A 49-year-old female patient with complaint of vulvar swelling attended for gynecologic evaluation to the hospital. The physical examination verified vulvar lesion as well as inguinal lymph nodes. The pathologic example was obtained and additional F-18 FDG PET/CT examination was performed with the suspicion of pelvic malignancy. The imaging was performed after fasting for 6 h and 11 mCi radiopharmaceutical injection as a whole body examination in the craniocaudal direction by PET/CT scanner (Siemens MCT). The imaging showed multiple enlarged hypermetabolic lymph nodes all over the body, pulmonary nodules, kidney, bone, and spleen lesions as well as vulvar hypermetabolic lesion. Whole-body horizontal PET and CT-fused image [Figure 1a] and transaxial plane image of vulva [Figure 1b]. Lymphoma involvement of the vulva is an extremely rare condition. There are several case reports presented in the literature previously.[1234] F-18 FDG PET/CT images of a patient with vulva involvement were presented as a case report;[5] however, in that case, the lesion was as a single vulvar lesion. This presented case report showed multiple organ involvement of lymphoma with unexpected presentation of vulvar lesion. F-18 FDG: 18F-fluorodeoxyglucose, PET/CT: Positron emission tomography computerized tomography](/content/210/2024/39/4/img/IJNM-39-318-g001.png)
![The pathology results showed B-cell diffuse large cell high-grade lymphoma as shown by the image (H and E, ×200), [Figure 2] Pathology results revealed Large B Cell Lymphoma diagnosis](/content/210/2024/39/4/img/IJNM-39-318-g002.png)
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
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