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Assessment of early response to treatment in extrapulmonary tuberculosis: Role of FDG-PET
Address for correspondence: Dr. Manjusha Yadla, SVIMS, Tirupati, Andhra Pradesh, India. E-mail: manjuyadla@gmail.com
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This article was originally published by Medknow Publications & Media Pvt Ltd and was migrated to Scientific Scholar after the change of Publisher.
Sir,
We report an elderly man on dialysis who was evaluated for a suspected bronchogenic carcinoma with fluorodeoxyglucose positron emission tomography (FDG-PET) computed tomography (CT) scan. His scan revealed multiple mediastinal lymph nodes and skeletal lesions [Figure 1] which were later confirmed to be tuberculosis (TB) on TB PCR, Lowenstein–Jensen medium. Three days after initiation of anti-tubercular therapy (ATT), metabolic activity in lymph nodes decreased significantly [Figure 2] though the skeletal lesion activity persisted. Three months after ATT, there was complete resolution of both lymph nodal and skeletal lesions [Figure 3]. Earliest response to ATT on FDG-PET CT was reported to be at the end of eight-week therapy.[1] FDG-PET/CT is the imaging modality that is useful in detecting extra-pulmonary TB and also in assessment of early response to ATT as early as 3 days.
REFERENCE
- FDG-PET/CT in diagnosis and early response evaluation of extra-pulmonary tuberculosis in a patient with aplastic anemia. J Postgrad Med. 2010;56:219-21.
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